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Verapamil is a calcium channel blocker with a dual action on the heart and blood vessels, making it useful across a broader range of cardiovascular conditions than most calcium channel blockers in current use. Verapamil tablets are a prescription-only medicine used in adults for hypertension treatment, angina support, and heart rhythm management. VERAPAMIL (ver AP a mil) treats high blood pressure and prevents chest pain (angina). It works by relaxing the blood vessels, which helps decrease the amount of work your heart has to do. It belongs to a group of medications called calcium channel blockers. Compare prices and print coupons for Verapamil ER and other drugs at CVS, Walgreens, and other pharmacies. Prices start at $24.00 It works by relaxing the blood vessels, which helps decrease the amount of work your heart has to do. It belongs to a group of medications called calcium channel blockers. Take this medication by mouth. 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