Xifaxan is a rifamycin which works by killing bacteria that causes infection. The most common form of Xifaxan is a 550mg tablet. It is also available as a 200mg tablet. There are currently no generic alternatives for Xifaxan. It is covered by some Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower. Xifaxan Prices, Coupons, Copay Cards & Patient Assistance Prices Coupons Patient assistance Xifaxan (rifaximin) is a member of the miscellaneous antibiotics drug class and is commonly used for Diarrhea, Hepatic Encephalopathy, Irritable Bowel Syndrome, and others. The cost for Xifaxan 550 mg oral tablet is around $4,339 for a supply of 60 tablets, depending on the pharmacy you visit. Quoted … Get the facts on cost and Xifaxan, how the generic compares with the brand name, what financial assistance may be available, and more. Find information about patient assistance and insurance coverage for Xifaxan for IBS-D. See Important Safety Info and Full Prescribing Information. Xifaxan is a prescription drug used to treat some types of diarrhea and certain other conditions. Learn about the drug's cost, how to find savings, and more. With insurance, Xifaxan often ranges from $0 to $100+ per fill, but plan design, dose, and copay cards can drop your share to near $0. Find information about patient assistance and insurance coverage for Xifaxan for adults with Overt Hepatic Encephalopathy. See Safety and Full Prescribing Information. Use the price with your insurance or without — whichever is cheaper. Lookup XIFAXAN → NeedyMeds Independent nonprofit directory of patient assistance programs, copay cards, and charity co-pay foundations. Search for rifaximin → RxAssist PAP directory maintained by Volunteers in Health Care at Brown University. Free, no ads. Search PAPs → Patients commonly see price ranges for Xifaxan (rifaximin) that vary by dosage form, quantity, and insurance coverage. This article outlines typical costs, price drivers, and practical budgeting estimates for a 14-day course. The goal is to provide concrete cost information to help with planning and comparisons. 3 Humana plans that cover Xifaxan. Check formulary tier, step therapy, prior auth requirements, and copay estimates for each plan. Xifaxan without insurance costs $70 per tablet, or $421 for six 550 mg tablets. Here's how to save. Palmetto Pharm Insurance coverage, deductibles, and refill frequency all affect long-term spending. A structured comparison can help patients make confident and informed decisions about affording Xifaxan medication. How to Buy Xifaxan Online Safely Many patients choose to buy Xifaxan online to compare pricing. Xifaxan can be expensive for some people, even with insurance. You may be eligible for Xifaxan coupons, savings cards, low-income subsidies, and patient assistance programs that may help reduce your out-of-pocket costs. palmettopharm.com As seen in the table, the cost of Xifaxan can be quite high, especially if you are purchasing it without insurance. However, by using coupons, insurance, or opting for a generic version like Rifaximin, you can significantly lower your out-of-pocket expenses. Xifaxan Generic Cost: Save with Rifaximin One of the most effective ways to save on your Xifaxan prescription is to purchase its generic … Currently, the average cost of Xifaxan without insurance ranges from $2000 to $3450 for a 30-day supply, depending on dosage and quantity prescribed. With insurance, most patients can access it with copays lower than $100. Medicare prescription drug plans usually cover Xifaxan. Learn about coverage options, cost, and cost-savings programs. Image: How much does Xifaxan cost with insurance? Xifaxan costs may vary depending on the individual's insurance coverage. The exact cost depends on factors such as health plan, deductible, and pharmacy chosen. Most insurance plans cover at least a portion of Xifaxan's cost; however, it is recommended to check with the health insurer prior to purchase in order to determine out-of-pocket … First off, getting Xifaxan approved by your insurance company. I ended up getting for free a medication that would have cost me over $3,000 out of pocket! So yes the insurance companies will put up a good fight to deny this medication even using ridiculous excuses like, have you tried other anti-depressants?? Xifaxan is a brand-name drug that treats conditions like IBS-D and traveler's diarrhea. Without insurance, it costs about $2,000 per month, but no generic is available. Most health insurance plans, including Medicare Part D and Medicaid, cover Xifaxan. Restrictions such as prior authorization, quantity limits, and high out-of-pocket costs may … Get the best price on Xifaxan at pharmacies near you with SingleCare. Save up to 80% with our Xifaxan coupons – with or without insurance! Medicare Part D usually covers the cost of Xifaxan (rifaximin). Learn more about Medicare's prescription drug coverage here. Xifaxan cost runs $2,350-$3,950 for 60 tablets at U.S. retail in 2026. See real prices by condition, what the new generic means, and how to pay less. The cost of Xifaxan (Rifaximin) without insurance is approximately $2586 for sixty 550-mg tablets [1]. This cost is based on the average retail cost of the… XIFAXAN® (rifaximin) 550 mg tablets are indicated for the reduction in risk of overt hepatic encephalopathy recurrence and for the treatment of IBS-D in adults. See Important Safety Information and full Prescribing Information on website. Overview Rifaximin can cost over $2,000 without insurance. Learn how to save with coupons, discount cards, the Xifaxan Savings Card, and patient assistance programs. Get the best price on your medication with our always-free coupon card. No Medfinder search required. Get your free card … Discount only — not insurance. With the XIFAXAN Savings Card, most eligible patients* with commercial insurance and coverage for XIFAXAN may pay as little as $0 for their XIFAXAN prescription. Xifaxan in 2026 too expensive? Find manufacturer coupons, pharmacy discounts, generic options, and the best prices at pharmacies near you on Medfinder. Reduce Xifaxan costs to $80/month with the Patient Assistance Program. Reliable support for digestive and infection-related conditions. Xifaxan (rifaximin) Savings – ordering the generic from abroad With Xifaxan projected to enjoy patent protection until 2029, cost relief through generic competition isn't exactly around the corner domestically. However, the generic is available to order online from pharmacies located overseas, specifically in India. What is the average cost of Xifaxan per month without insurance? Without insurance, the monthly cost of Xifaxan can range from approximately $105 to $150, depending on the pharmacy and location. Prices are estimates, vary by pharmacy, ZIP and day, and either source can be lower on a given day. See current prices on the RxDiff drug page. Xifaxan contains rifaximin and is a prescription tablet. What someone pays without insurance depends on strength, quantity, pharmacy, ZIP code, and current coverage or program terms. The Quick Answer Xifaxan is not FDA-approved for SIBO treatment, which is why many insurance plans don't initially cover it, though your doctor may be able to request coverage through a specific pathway outlined in your denial letter. Xifaxan is only available as a brand-name medication costing around $55 per tablet, making a typical 14-day course cost at least $2,300, with little variation in … Find resources to help you better understand overt hepatic encephalopathy like a symptom checklist, FAQs, and videos. See Safety and Full Prescribing Information. Why is Xifaxan not covered by insurance? Xifaxan (rifaximin) is an expensive brand-name antibiotic that is used to treat irritable bowel syndrome with diarrhea (IBS-D), traveler's diarrhea, and hepatic encephalopathy. XIFAXAN® (rifaximin) 550 mg tablets are indicated for the reduction in risk of overt hepatic encephalopathy (OHE) recurrence in adults5. When a PA is required for XIFAXAN, be sure that all information is included and accurate. Transfer your prescription for XIFAXAN 550 MG TAB on Amazon Pharmacy. FREE SHIPPING for Prime members. INSTRUCTIONS FOR USE The following Coverage Policy applies to health benefit plans administered by Cigna Companies. Certain Cigna Companies and/or lines of business only provide utilization review services to clients and do not make coverage determinations. References to standard benefit plan language and coverage determinations do not apply to those clients. Coverage Policies are intended to …