Xifaxan without insurance costs $70 per tablet, or $421 for six 550 mg tablets. Here's how to save. Xifaxan prices from $416.75. Compare mail-order and cash prices at 60,000+ US pharmacies with a free Rx.com coupon — no insurance needed. Without insurance or discounts, the total retail cost of treatment would be more than $3,000. To prevent overt hepatic encephalopathy, a condition where toxins from the liver reach the brain and cause neurological symptoms, 550 mg of Xifaxan is taken two times per day for as long as necessary. The cost for Xifaxan 550 mg oral tablet is around $4,339 for a supply of 60 tablets, depending on the pharmacy you visit. Quoted prices are for cash-paying customers and are not valid with insurance plans. Xifaxan is a rifamycin which works by killing bacteria that causes infection. The most common form of Xifaxan is a 550mg tablet. It is also available as a 200mg tablet. There are currently no generic alternatives for Xifaxan. It is covered by some Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower. Find today's lowest Xifaxan price. Compare coupons, discount cards, savings programs and pharmacy costs side by side, with or without insurance. Get the facts on cost and Xifaxan, how the generic compares with the brand name, what financial assistance may be available, and more. From the Guidelines The cost of Xifaxan (Rifaximin) without insurance is approximately $2586 for sixty 550-mg tablets 1. Cost Breakdown This cost is based on the average retail cost of the drug, as reported in a study published in the JAMA Network Open 1. Save on Xifaxan (rifaximin) prescription medication with Blink Pharmacy. Same pills. Lower prices. No coupon req. Xifaxan is a prescription drug used to treat some types of diarrhea and certain other conditions. Learn about the drug's cost, how to find savings, and more. How much would Xifaxan cost without insurance? Without insurance, a 30-day supply (90 tablets) of Xifaxan 550mg typically costs $5,000-$5,300 at U.S. pharmacies. In the United States, Xifaxan is widely prescribed due to its effectiveness and tolerability, but its cost can be high, especially for those without comprehensive insurance coverage. Below, we'll explore the uses, dosage, pricing, and potential ways to save on Xifaxan, including generic options and insurance coverage. The average cost is over $2500 for a 14-day course treatment (#42 tablets) of Xifaxan 550 mg. If your insurance company does not pay for Xifaxan, talk with your healthcare provider to see if there is an alternative drug that is covered that might be right for you. The price without insurance can vary depending on the pharmacy. Check with your local pharmacy to determine the total cost of your prescription without insurance. If you don't have insurance, you can use a Xifaxan coupon from SingleCare to potentially reduce your out-of-pocket expenses to $425.35 for 6, 550mg tablet. Currently, the average cost of Xifaxan without insurance ranges from $2000 to $3450 for a 30-day supply, depending on dosage and quantity prescribed. With insurance, most patients can access it with copays lower than $100. We would like to show you a description here but the site won't allow us. How much does Xifaxan cost without insurance? With an average retail price of $2,000 for 30 pills, Xifaxan 550 mg tablets average about $66 each. Fortunately, most people will not need months of treatment. Traveler's diarrhea requires twice-daily dosing for three days (six tablets). IBS-D requires three tablets a day for 14 days (42 tablets). Hepatic encephalopathy does not have an … The Xifaxan cost in the United States is often high, with many patients paying thousands for a short course. Understanding why it costs so much and what legal savings options exist can help patients and providers plan smarter treatment decisions. Research shows that the average cost of rifaximin for IBS-D is $1,250.76 for a two-week course with insurance, and the total cost can approach $3,000 … Xifaxan (rifaximin) Savings – ordering the generic from abroad With Xifaxan projected to enjoy patent protection until 2029, cost relief through generic competition isn't exactly around the corner domestically. However, the generic is available to order online from pharmacies located overseas, specifically in India. We would like to show you a description here but the site won't allow us. Palmetto Pharm Compare generic Xifaxan (rifaximin) 550 mg prices from verified online pharmacies or local U.S. pharmacies. Free coupons for generic Xifaxan (rifaximin). Discounts up to 80% off the retail price. Medicare coverage and pricing details for Xifaxan. Learn more about Medicare prescription drug plans and savings with GoodRx. The Real Cost of Xifaxan Without Insurance: A Comprehensive Guide Without insurance, Xifaxan, a brand-name medication used primarily to treat traveler's diarrhea, hepatic encephalopathy, and irritable bowel syndrome with diarrhea (IBS-D), can be a significant financial burden. Expect to pay between $700 and $900 for a 200mg, 30-tablet supply when paying the full retail price. How much does Xifaxan cost without insurance? Without insurance, Xifaxan 550 mg costs approximately $1,600 to $2,200 for a 30-day supply (60 tablets) for hepatic encephalopathy. Xifaxan cost runs $2,350-$3,950 for 60 tablets at U.S. retail in 2026. See real prices by condition, what the new generic means, and how to pay less. Overview Rifaximin can cost over $2,000 without insurance. Learn how to save with coupons, discount cards, the Xifaxan Savings Card, and patient assistance programs. Get the best price on your medication with our always-free coupon card. No Medfinder search required. Get your free card … Discount only — not insurance. Find information about patient assistance and insurance coverage for Xifaxan for IBS-D. See Important Safety Info and Full Prescribing Information. Image: How much does Xifaxan cost without insurance? Xifaxan typically costs between $1,000 and $2,500 without insurance. The exact cost will depend on the dosage and number of pills prescribed by a doctor. Prices may also vary depending on where it is purchased. Generic versions of Xifaxan may be more affordable than brand-name options. Find information about patient assistance and insurance coverage for Xifaxan for adults with Overt Hepatic Encephalopathy. See Safety and Full Prescribing Information. What is the average cost of Xifaxan per month without insurance? Without insurance, the monthly cost of Xifaxan can range from approximately $105 to $150, depending on the pharmacy and location. First off, getting Xifaxan approved by your insurance company. I ended up getting for free a medication that would have cost me over $3,000 out of pocket! So yes the insurance companies will put up a good fight to deny this medication even using ridiculous excuses like, have you tried other anti-depressants?? How much does Xifaxan cost with The Rx Advocates? With The Rx Advocates, patients pay a fixed monthly service fee, which depends on the number of medications covered. 1 Medication (Xifaxan only) – $80 per month 2 Medications (Xifaxan + 1 other) – $90 per month 3 Medications (Xifaxan + 2 others) – $100 per month 4+ Medications – $110 per … Currently the lowest price for Xifaxan is $2803.76 on SaveHealth. Save money using our free Xifaxan coupons. Compare prices at pharmacies near you for different prescriptions. Check the cost and show the pharmacist our Xifaxan savings card to get your discount. Image: How much does Xifaxan cost with insurance? Xifaxan costs may vary depending on the individual's insurance coverage. The exact cost depends on factors such as health plan, deductible, and pharmacy chosen. Most insurance plans cover at least a portion of Xifaxan's cost; however, it is recommended to check with the health insurer prior to purchase in order to determine out-of-pocket … palmettopharm.com How Much Does Xifaxan Cost Without Insurance in 2026? Without insurance, Xifaxan (rifaximin) is generally considered a high-cost prescription medication in the U.S. How Much Does Xifaxan Cost Without Insurance Prices vary by pharmacy and can change. Compare a current quote for your exact prescription on the RxDiff Xifaxan page. Ask your pharmacist to confirm the current quote and applicable terms for your prescription. RIFAXIMIN (ri FAX i men) treats diarrhea caused by bacteria. It may also be used to treat irritable bowel syndrome (IBS) with diarrhea. It can be used to prevent hepatic encephalopathy, a condition where the liver does not clear toxins from the body. It works by killing or preventing the growth of bacteria in your intestines that make toxins. It belongs to a group of medications called …